“Neural crest identity along the body axis”
Chair: Anne-Hélène Monsoro-Burq (Institut Curie, France)
Chair: Gerhard Schlosser (University of Galway, Ireland)
• 17:10 – 17:15 Gerhard Schlosser: Introduction
• 17:15 – 17:45 Anestis Tsakiridis (University of Sheffield, UK) “Anteroposterior patterning of human neural crest cells in vitro”
• 17:45 – 18:00 Ruth Williams (University of Manchester, UK) “Chromatin remodeller Chd7 is developmentally regulated in the neural crest by tissue-specific transcription factors”
• 18:00 – 18:15 Subham Seal (Institut Curie, France) “Transcriptional regulator Prdm12 regulates neural crest cell EMT and migration”
• 18:15 – 18:30Coffee Break
• 18:30 – 19:00 Filippo Rijli (Friedrich Miescher Institute for Biomedical Research, Switzerland) “Shaping Faces by 3D Genome Regulation”
• 19:00 – 19:15 Merin Lawrence (University of Galway, Ireland) “Analysing the role of SOX9/10 in Xenopus neural crest and placodes”
Chair: Igor Adameyko (Medical University of Vienna, Austria)
• 19:15 – 19:20 Igor Adameyko: Introduction
• 19:20 – 19:35 Irina Poverennaya (Medical University of Vienna, Austria) “rRNA-modifications connect mesenchymal fate selection in neural crest and prognosis in neuroblastoma”
• 19:35 – 19:50 Maëlys Andre (MeLis Unit, University Lyon 1, France) “Dynamics of axon guidance transcriptional programs directing early differentiation of vagal neural crest-derived enteric neurons”
• 19:50 – 20:05 Aleksandr Kotov (Institut Curie, France) “Exploring the neural border and neural crest gene regulatory networks in Xenopus with single cell transcriptomes”
• 20:05 – 20:15 Flash talks:
Chenxi Zhou (Institut Curie, France) “Mapping transcription of the EMT-TFs during neural crest development”
Michael Eibl (Heidelberg University, Germany) “Elucidation of transcriptional regulation underlying human neural crest cell differentiation by integration of time-course CAGE- and ATAC-seq data”
Chair: Karen Liu (King’s College London, UK)
• 09:00 – 09:05 Karen Liu: Introduction
• 09:05 – 09:35 Eric Theveneau (University of Toulouse, France) “Non-canonical regulation of neural crest EMT by matrix metalloproteinases”
• 09:35 – 09:50 Sydney Arlis (University of Iowa, USA) “Defining the role of ISM1 in craniofacial development”
• 09:50 – 10:05 Anna Wulf (King’s College London, UK) “Pathological function of ALK and GSK3 in neural crest migration”
• 10:05 – 10:20 Nioosha Nekooie Marnany (Institut de Biologie de l’Ecole Normale Supérieure, France) “Non-canonical nuclear function of glutaminase drives EMT during neural crest cell development”
• 10:20 – 11:00 Coffee Break
• 11:00 – 11:30 Angela Nieto (Instituto de Neurociencias, CSIC-UMH, Spain) “Epithelial plasticity trajectories in neural crest, fibrosis and cancer”
• 11:30 – 11:45 Stina Andersson (Lund University, Sweden) “Micro-environmental regulation of cancer cell fate plasticity”
• 11:45 – 12:00 Nitin Narwade (Instituto de Neurociencias, CSIC-UMH, Spain) “GRNs prediction and in silico perturbation of EMT trajectories”
• 12:00 – 12:15 Stefanie Gossen (Philipps University Marburg, Germany) “The Rho GEF Trio is transported by microtubules and affects microtubule stability in migrating neural crest cells”
• 12:15 – 12:25 Flash talks:
Carmen Moreno Gonzalez (The Francis Crick Institute & King’s College London, UK) “Neurocrestoids on-a-chip: a 3D bioengineered platform to study neural crest delamination and migration”
Alek Erickson (Karolinska Institut, Sweden) “Motor nerves direct the development of the sympathetic nervous system”
Ho Yin Pang (The University of Hong Kong, Hong Kong) “Elucidating The Mechanistic Role of STRAP In Regulating SNAI2 Stability for Proper Onset of Cranial Neural Crest Epithelial-Mesenchymal
Transition”
Chair: Erin Knock (Stemcell Technologies, Canada)
• 14:30 – 14:35 Erin Knock: Introduction
• 14:35 – 15:05 Ruth Palmer (University of Gotehnburg, Sweden) “When neural crest development goes wrong – the role of the ALK receptor tyrosine kinase in neuroblastoma”
• 15:05 – 15:20 Ayat Ahmed (Heidelberg University, Germany) “NR2F1 in neural crest cells: a novel approach to model Bosch-Boonstra-Schaaf Optic Atrophy Syndrome (BBSOAS)”
• 15:20 – 15:35 Ana Filipa Duarte (Erasmus Medical Center, Netherlands) “Gene discovery and in vitro modelling of craniosynostosis, a neurocristopathy”
• 15:35 – 15:50 Francesca Lorenzini (Azelead, France) “Melanoma innervation is associated with cancer progression in a zebrafish xenograft model”
• 15:50 – 16:30 Round table discussion
• 16:30 – 17:30 Group photo, Coffee Break and Poster session
Chair: Nadège Bondurand (Institut Imagine, France)
• 09:00 – 09:05 Nadège Bondurand: Introduction
• 09:05 – 09:35 Maria Eleni Kastriti (Medical University of Vienna, Austria) “Using single cell transcriptomics to redefine Schwann cell precursor states”
• 09:35 – 09:50 Jholy De La Cruz (IRMB Montpellier, France) “Neural crest cells role during mouse embryo limb bud regeneration”
• 09:50 – 10:05 Chloé Paka (Stem Cell Technolgies/King’s College London, UK) “Using hPSCs to model ALK-mediated neuroblastoma”
• 10:05 – 10:20 Amy Kerr (University of East Anglia, UK) “Of dots and lines: Characterising the development of the adrenal gland in Xenopus”
• 10:20 – 10:40 Flash Talks:
Elise Marechal (Aix-Marseille University, France) “Braf-mutant Schwann cells transdifferentiate to a repair phenotype to cause congenital demyelinating neuropathy in mice”
Liu Ziwei (Karolinska Institut, Sweden) “Spatio-temporal Analysis of the Enteric Nervous System Development using Single-cell RNA-sequencing”
Margaux Sivori (Institut de Biologie de l’Ecole Normale Supérieure, France) “The pelvic organs receive no parasympathetic innervation”
Kenza Cheriet (Institut Jacques Monod, France) “Tumorigenic transformation of neural embryonic cells by oncoRAS associated to Rhabdsomyosarcoma”
Andrius Cesiulis (University of California, USA) “Neurogenesis Potential in Enteric Nervous System Progenitor Cells”
• 10:40 – 11:15 Coffee Break
• 11:15 – 11:30 Frida Sanchez Garrido (Museum national d’Histoire naturelle, France) “Pleiotropic role for Dlx5/6 transcription factors in the formation of the mammalian acoustic system”
• 11:30 – 11:45 Tanya Shaw (King’s College London, UK) “Facial dermal fibroblasts have distinct characteristics potentially reflecting their neural crest developmental origins”
• 11:45 – 12:00 Martina Orefice (University of Pisa, Italy) “Zebrafish for Pitt-Hopkins syndrome: studying the TCF4 role in craniofacial development”
Chair: Grant Wheeler (University of East Anglia, UK)
• 14:30 – 14:35 Grant Wheeler: Introduction
• 14:35 – 15:05 Nadège Bondurant (Institut Imagine, France) “Control of enteric nervous system, melanocytes and Schwann cells development: from HSCR and WS genes identification to A to I RNA editing regulation”
• 15:05 – 15:20 Marco Antonaci (University of East Anglia, UK) “Getting your eye in shape: the dual role of miR-204-1 in eye development”
• 15:20 – 15:50 Lukas Sommer (University of Zurich, Switzerland) “Tumors are wounds that never heal: the role of adult NCSC-like cells in wound repair and skin tumor formation”
• 15:50 – 16:20 Coffee Break
• 16:20 – 16:50 Charlotte Ashby (Trustee of Headlines Craniofacial Support, UK) “Living with Neurocritopathies”
• 16:50 – 17:05 Sarah Gerstner (Philipps-University Marburg, Germany) “FBRSL1, a gene causative for a congenital malformation syndrome, is required for Xenopus craniofacial and heart development”
• 17:05 – 17:20 William Bertani Torres (Institut Imagine, France) “Waardenburg syndrome: from SOX10 to a candidate gene”
• 17:20 – 17:35 Casey Griffin (New York University, USA) “Teasing apart the role of SF3B4 in Nager syndrome: a tale of frogs and embryonic stem cells”